Jobelyn<sup>&reg;</sup>, a Sorghum-Based Nutritional Supplement Attenuates Unpredictable Chronic Mild Stress-Induced Memory Deficits in Mice
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منابع مشابه
Jobelyn®, a Sorghum-Based Nutritional Supplement Attenuates Unpredictable Chronic Mild Stress-Induced Memory Deficits in Mice
The ability of an organism to adapt to aversive stressful situations or life challenging circumstances is very crucial to its state of health and survival. However, breakdown in adaptation due to persistent uncontrollable stress, leads to impairment of bodily functions and onset of a variety of pathological disorders especially memory decline. This study was designed to evaluate the effect of J...
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Stress is an important precipitant factor for depression. Changes in various body systems that occur in depression are similar to those observed in response to stress. Chronic stress may alter behavioral, neurochemical and physiological responses to drug challenges and novel stressors. Unpredictable chronic mild stress (UCMS) also produces alteration in the serotonergic (5-HT; 5-hydroxytryptami...
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Major depression is a complex psychiatric disorder characterized by affective, cognitive, and physiological impairments that lead to maladaptive behavior. The high lifetime prevalence of this disabling condition, coupled with limitations in existing medications, make necessary the development of improved therapeutics. This requires animal models that allow investigation of key biological correl...
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OBJECTIVE Chronic stress is an important risk factor for atherosclerotic diseases. Our previous studies have shown that chronic unpredictable mild stress (CUMS) accelerates atherosclerosis and up-regulates TLR4/NF-κB expression in apoE-/- mice. However, TLR4/NF-κB signaling whether directly contributes to the development of atherosclerosis in CUMS mice is unclear. We hypothesized that the inter...
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Introduction: Long-term stress disturbs HPA axis and increases glucocorticoids release, which disturbs neural plasticity in the hippocampus and may lead to learning and memory deficits. Noticeably, vitamin D plays a protective role in the nervous system and has receptors in the hippocampus. This behavioral study investigates the possible protective role of vitamin-D against the negative effects...
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ژورنال
عنوان ژورنال: Journal of Behavioral and Brain Science
سال: 2015
ISSN: 2160-5866,2160-5874
DOI: 10.4236/jbbs.2015.513056